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Cerebral Oedema and Increased Intracranial Pressure in Chronic Liver Disease
Lancet 351:719-721, Donovan,J.P.,et al, 1998
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Article Abstract
All the patients had intracranial hypertension and cerebral edema.Two patients had successful treatment of cerebral hypertension with improvement of intracranial pressure such that orthotopic liver transplantation was undertaken.Both patients became neurologically normal after transplantation.Eight patients had only a transient response to treatment and died of cerebral edema before a transplant could be done. Cerebral edema and increased intracranial pressure can occur in chronic liver disease and presents as neurological deterioration.Treatment guided by monitoring of intracranial pressure can lead to the reversal of intracranial hypertension but in most patients,cerebral edema contributes to death or places them at too high a risk for liver transplantation.
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cerebral edema
cerebral edema,origin and treatment
decerebrate posture
decorticate posture
hepatic encephalopathy
hepatic failure
intracranial pressure,increased
intracranial pressure,increased,treatment of
liver disease
liver transplantation
mortality
prognosis
treatment of neurologic disorder
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