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Sensitivity and specificity of 201TI-SPECT in depicting lymphoma were 100% and 93%,respectively,based on the initial qualitative analysis.Fifty-one patients had positive 201TI-SPECT results,of whom 43 were determined to have lymphoma(four by biopsy/autopsy,39 by clinical and radiologic findings).Upon reevaluation with both a quantitative and qualitative approach,those studies initially interpreted as positive in patients without lymphoma(false positives)were found to be negative.Brain 201TI- Spect is an effective study in the diagnosis of CNS lymphoma in AIDS patients.Specificity can be increased by routinely performing a quantitative analysis of all lesions. |
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