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Serotonin Syndrome Induced by Transitioning from Phenelzine to Venlafaxine:four Patient Reports
Neurol 51:274-276, Diamond,S.,et al, 1998
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Article Abstract
With the use of the newer antidepressants beyond the traditional tricyclics and monoamine oxidase inhibitors,newer options in headache prophylaxis are provided as well as the potential for undesirable and even potentially life-threatening interactions between medications.In this article,four patient reports of a specific interaction-the serotonin syndrome-are presented.These events resulted from transitioning headache patients from on older antidepressant(phenelzine)to a newer antidepressant (venlafaxine).
 
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adverse drug reaction
antidepressant
drug interactions
monoamine oxidase inhibitors
phenelzine
serotonin syndrome
venlafaxine

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