[home]
[thesaurus]
Click Here to return To Results
CAG Repeat Number Correlates with the Rate of Brainstem and Cerebellar Atrophy in Machado-Joseph Disease
Neurol 51:882-884, Abe,Y.,et al, 1998
See this aricle in Pubmed
Article Abstract
We compared the CAG repeat length and the severity of the brainstem and cerebellar atrophy visualized by MRI in 30 patients with Machado-Joseph disease.We found a strong correlation between the CAG repeat number and the quotient of the degree of atrophy divided by age at examination.These results suggest that the rate of disease progression is dependent on the CAG repeat size and disease progression may commence at birth.
Related Tags
(click to filter results - removes previous filter)
brainstem,atrophy
CAG repeats
cerebellar atrophy,primary
MRI
MRI,abnormal
prognosis
spinocerebellar ataxia
spinocerebellar ataxia type 3/Machado Joseph disease
trinucleotide repeats
Click Here to return To Results