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Recombinant Human Nerve Growth Factor in the Treatment of Diabetic Polyneuropathy Neurol 51:695-702, 6621998., Apfel,S.C.,et al, 1998 See this aricle in Pubmed Article Abstract Compared with placebo,recombinant human nerve growth factor led to significant improvement after six months of treatment,as measured by the sensory component of the neurologic examination,two quantitative sensory tests,and the impression of most subjects that their neuropathy had improved.Three prospectively identified multiple endpoint analyses indicated improvements in the nerve growth factor treatment groups over the placebo group in all three analyses(p=0.032;p=0.008;p=0.005). Recombinant human nerve growth factor was well tolerated,with injection site discomfort reported as the most frequent adverse event.Recombinant human nerve growth factor appears to be safe and shows preliminary evidence of efficacy in patients with symptomatic diabetic polyneuropathy.

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(click to filter results - removes previous filter) diabetes mellitus diabetes mellitus,neurologic manifestations of nerve growth factor neuropathy neuropathy,diabetic neuropathy,peripheral,treatment treatment of neurologic disorder

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