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The Effects of Mannitol on Cerebral Edema after Large Hemispheric Cerebral Infarct Neurol 52:583-587, Manno,E.M.,et al, 1999 See this aricle in Pubmed Article Abstract Acute mannitol used in patients with cerebral edema after a large hemispheric infarction does not alter midline tissue shifts or worsen neurologic status.

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