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Overall, we found 16 aneurysms in 10 of 125 relatives (8%; 95% CI, 4 to 14%). Of the nine patients with previous surgery for ruptured or unruptured intracranial aneurysms, three had new aneurysms. Two factors were associated with a significantly higher risk of intracranial aneurysms: 1) a history of treatment for ruptured or unruptured intracranial aneurysms (relative risk 5.5; 95% CI, 1.7 to 17.8) and 2) having three or more affected relatives (relative risk 3.3; 95% CI, 1.0 to 10.6). Siblings tended to have a higher risk of intracranial aneurysms than did children of SAH patients, although the difference was not significant. Because the yield is high, screening is recommended in first-degree members of families with familial SAH. Repeated screening should be considered in relatives who have been treated for familial intracranial aneurysms. |
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aneurysm
aneurysm,intracranial
aneurysm,intracranial,familial
aneurysm,intracranial,screening for
CAT scan
CAT scan,angiography
familial
genetic neurologic disorders
MRI
MRI,abnormal
MRI,angiography
prognosis
subarachnoid hemorrhage
subarachnoid hemorrhage,familial
subarachnoid hemorrhage,prognosis
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