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Progressive Multifocal Leukoencephalopathy and Human Immunodeficiency Virus-associated White Matter Lesions in AIDS:Magnetization Transfer MR Imaging
Radiology 210:539-543, Ernst,T.,et al,, 1999
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Article Abstract
To determine the magnetization transfer features of progressive multifocal leukoencephalopathy (PML) and human immunodeficiency virus (HIV)-associated white matter lesions (WML) hereafter, HIV-WML on magnetic resonance (MR) images obtained in patients with acquired immunodeficiency syndrome (AIDS). The larger reduction in mangetization transfer ratio for PML lesions is most likely due to demyelination, whereas the reduction in HIV-WML may be associated primarily with gliosis. PML lesions appear to cause strong reductions in magnetization transfer ratio early in the course of disease. Magnetization transfer MR imaging is a noninvasive tool that improves the differentiation between PML and HIV-WML in patients with AIDS.
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acquired immunodeficiency syndrome
encephalitis
encephalitis,human immunodeficiency virus type 1
human immunodeficiency virus type 1
MRI
MRI,abnormal
MRI,magnetization transfer sequence
neurologic disease,diagnoses of
progressive multifocal leucoencephalopathy
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