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Adult Brainstem Gliomas
Neurol 51:1136-1139, Landolfi,J.C.,et al, 1998
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Article Abstract
There were 23 patients identified but complete information was available in only 19 (12 males and 7 females). Patients ranged in age from 17 to 70 years (median 40 years). Twelve patients were treated with radiotherapy at diagnosis and seven were observed, three of whom received subsequent radiotherapy. Median survival is 54 months (range, 3 to 98 months) and the 5 year survival is 45%. There was a trend for patients with a higher performance status at diagnosis to have longer survival, but this did not reach statistical significance. Other factors did not affect survival. Adults with brainstem gliomas may survive significantly longer than children, suggesting the disease may be less aggressive in adults. Furthermore, some patients with a long duration of symptoms or tectal or cervicomedullary tumors may be managed initially with observation alone.
 
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