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Out of 24 infants, 19 had an infarction in the territory of a major cerebral vessel and 5 in the border zone between cerebral arteries. Neuromotor outcome was normal in 17 and abnormal in 7 infants. Of these 7 normal infants, 5 infants showed a definite hemiplegia, whereas the other 2 showed some asymmetry of tone or function but no definite hemiplegia. None of the adverse antenatal or perinatal factors was significantly associated with abnormal outcome. Neonatal clinical examination was not always predictive of the outcome. The extent of the lesion on MRI was a better predictor. In particular, it was the concomitant involvement of hemisphere, internal capsule and basal ganglia that was always associated with an abnormal outcome whereas the involvement of only one or two of the three tended to be associated with a normal outcome. EEG was also very helpful. Abnormal background activity either unilateral or bilateral was found in 6 infants and 5 out of 6 developed hemiplegia. In contrast, the presence of seizure activity in presence of a normal background was not related to abnormal outcome. Early MRI and EGG can help to identify the infants with cerebral infarction who are likely to develop hemiplegia. |
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cerebral infarction
cerebrovascular accident
cerebrovascular accident,neonatal
cerebrovascular accident,prognosis in
electroencephalogram
electroencephalogram,abnormalities of
hemiplegia
infantile hemiplegia
MRI
MRI,abnormal
prognosis
seizure
seizure,neonatal
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