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Hyperammonemia in Asterixis Induced by Carbamazepine:Two Case Reports
Acta Neurologica Scand 69:186-189, Ambrosetto,G.,et al, 1984
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Article Abstract
Two patients developed asterixis while they were taking carbamazepine at "therapeutic" levels. The only laboratory abnormality was slight hyperammonemia. It occurred with normal hepatic function as a dose-related effect. In fact, the blood ammonia level decreased and asterixis ceased when carbamzepine was stopped or reduced in dosage. The relationship between asterixis and hyperammonemia during carbamazepine therapy is discussed.
Related Tags
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adverse drug reaction
ammonia
anticonvulsants
anticonvulsants,untoward effects of
asterixis
carbamazepine
carbamazepine,toxicity
movement disorder
movement disorder,drug induced
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