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Primary Intracranial Neoplasms in Patients with HIV Neurol 52:1648-1651, Blumenthal,D.T.,et al, 1999 See this aricle in Pubmed Article Abstract Five of eight patients had a glioblastoma multiforme; other tumors included an anaplastic ependymoma, a low-grade glioma, a subependymoma, and a leiomyosarcoma. More than half of the patients developed their tumor >/= 6 years after the dia gnosis of HIV infection. Patient prognosis and survival was best predicted by tumor histology. Treatment response and outcome did not appear to be influenced by HIV infection. Only the leiomyosarcoma demonstrated evidence of latent EBV infection. HIV- infected patients are at risk for intracranial neoplasms other than PCNSL, and benefit from aggressive tumor-specific therapy. It is possible that gliomas are occurring at a higher rate than in the general population. There was no evidence of HIV or EBV infection in any glial tumor.

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(click to filter results - removes previous filter) acquired immunodeficiency syndrome astrocytoma glioblastoma multiforme(astrocytoma Gr.III) glioma glioma,low-grade human immunodeficiency virus type 1 neoplasm,primary intracranial neoplasm,primary of CNS

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