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Of the respondents, 87.3% reported having performed <200 operations and 9.7% reported 200 to 500 previous operations. The remaining 3 % reported more than 500 previous operations. More extensive previous experience with transsphenoidal surgery was associated with a greater likelihood of having witnessed each specific complication. The mean operative mortality rate for all three groups was 0.9%. Anterior pituitary insufficiency (19.4%) and diabetes insipidus (17.8%) were complications with the highest incidence of occurrence. The overall incidence of cerebrospinal fluid fistulas was 3.9%. Other significant complications, such as carotid artery injuries, hypothalamic injuries, loss of vision, and meningitis, occurred with incidence ra tes between 1 and 2%. An inverse relationship was found between the experience group and the likelihood of complications, as indicated by significant negative Spearman correlation coefficients for all but 2 of the 14 complications listed in the survey (P <0.05). Thus, increased experience with transsphenoidal surgery seems to be associated with a decreased percentage of operations resulting in complications. Some caution should be exercised in interpreting these data. |
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carotid artery injury carotid artery laceration cerebrospinal fluid,fistula diabetes insipidus hypothalamus,damage to iatrogenic neurologic disorders meningitis meningitis,iatrogenic microsurgery,transsphenoidal neoplasm,pituitary neoplasm,pituitary,treatment of neurologic complications of,surgery pituitary,adenoma pituitary,insufficiency of postoperative neurologic complications visual loss
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