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Identification of Major Ischemic Change, Diffusion-Weighted Imaging Versus Computed Tomography Stroke 30:2059-2065, Barber,P.A.,et al, 1999 See this aricle in Pubmed Article Abstract Sixteen of 17 patients had a final diagnosis of stroke. Acute ischemic changes were seen in all 16 on DWI (100% sensitivity) and in 12 of 16 on CT (75% sensitivity). DWI identified all 6 patients with major ischemia on CT, with excellent agreement between the 2 imaging techniques (kappa=0.88). One patient eligible for thrombolysis on the ECASS CT criteria had major ischemia on DWI. DWI is more sensitive than CT in the identification of acute ischemia and can visualize major ischemia mo re easily than CT.

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