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Effect of Liver Transplantation on Neurological Manifestations in Wilson Disease ArchNeurol 57:384-386, Stracciari,A.,et al, 2000 See this aricle in Pubmed Article Abstract A 44-year-old man with WD with cirrhosis and neurological symptoms (motor dysfunction and cognitive impairment) experienced a dramatic improvement in motor function early after LT, as well as normalization of copper balance and the disappe arance of Kayser-Fleischer rings. Abnormalities seen on magnetic resonance imaging scans were reversed 18 months after LT. Cognitive testing 2 years after LT showed a moderate global improvement. In this case, LT healed the neurological manifestations of WD. To date, this favorable result has been seen in almost 80% of cases. However, the decision to perform LT in patients with WD solely on the basis of neurological impairment must be considered experimental.

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(click to filter results - removes previous filter) basal ganglia,lesion,bilateral hepatolenticular degeneration(Wilson's disease) lenticular nucleus,lesion of,bilateral liver transplantation MRI MRI,abnormal treatment of neurologic disorder

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