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To reassess the independent risk factors for lacunar stroke and to clarify the role of potential embolic sources, we conducted a case-control study using transesophageal echocardiography and duplex ultrasonography. Among 62 consecutive pat ients with their first lacunar stroke and 202 normal co9ntrols, we found that hypertension (p<0.001), smoking (p=0.001), and aortic arch atheroma (p=0.006) were independently associated with an increased risk of lacunar stroke. Whether proximal aortic ar ch atheroma is mechanistically associated with lacunar stroke or merely coexistent is uncertain. |
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