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Balamuthia mandrillaris is a newly described pathogen that causes granulomatous amebic encephalitis, an extremely rare clinical entity that usually occurs in immunosuppressed individuals. We report a case of pathologically proven Balamuthia encephalitis with unusual laboratory and radiologic findings. A 52-year-old woman with idiopathic seizures and a 2-year history of chronic neutropenia of unknown cause had a subacute illness with progressive lethargy, headaches, and coma and died 3 months after the onset of symptoms. |
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brain biopsy,false negative central nervous system,infection of coma encephalitis encephalitis,amebic encephalitis,balamuthia headache hypoglycorrhachia immunosuppression meningoencephalitis meningoencephalitis,amoebic MRI MRI,abnormal MRI,ring sign
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