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Magnetic Resonance Imaging in the Clinical Diagnosis of Creutzfeldt-Jakob Disease Arch Neurol 57:1751-1757, Schroter,A.,et al, 2000 See this aricle in Pubmed Article Abstract Bilateral symmetric, high signal on T2-weighted MRIs were present in the basal ganglia of 109 (67%) of 162 patients with CJD. In the control group, which consisted of non-CJD dementia patients, these abnormalities on T2-weighted MRIs were f ound in 4 (7%) of 58 patients. This corresponds to a high specificity in the differential diagnosis of CJD. These results indicate that MRI is a useful and valuable tool with reasonable sensitivity (67%) and high specificity (93%) and should be consider ed as an additional cornerstone in the clinical diagnosis of CJD.

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