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Evaluation of CSf-tau and CSF-AB42 as Diagnostic Markers for Alzheimer Disease in Clinical Practice
Arch Neurol 58:373-379,349, Andreasen,N.,et al, 2001
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Article Abstract
Cerebrospinal fluid tau and CSF-A(42 have so far been studied in research settings under conditions providing data on the optimal performance. WE examined a prospective patients sample, with assays run in clinical routine giving figures clo ser to the true performance of CSF-tau and CSF-A(42. The predictive value for AD was greater than 90%. Therefore, these biomarkers may have a role in the clinical workup of patients with cognitive impairment, especially to differentiate early AD from no rmal aging and psychiatric disorders.
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Alzheimer's disease
Alzheimer's disease,diagnosis of
amyloid
amyloid beta protein
cerebrospinal fluid
cerebrospinal fluid,abnormal
dementia,diagnostic evaluation of
neurologic disease,diagnoses of
tau protein
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