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Is Carbamazepine Teratogenic? A Prospective Controlled Study of 210 Pregnancies Neurol 57:321-324, Diav-Citrin,O.,et al, 2001 See this aricle in Pubmed Article Abstract The Israeli Teratogen Information Service prospectively followed up 210 pregnancies with first trimester carbamazepine exposure. Pregnancy outcome was compared with that of two overlapping controls, matched and general (n = 629), exposed to nonteratogenic agents. Our study suggests a twofold increase in the rate of major congenital anomalies (12/160 [carbamazepine] versus 18/560 [general control]; relative risk 2.24; 95% CI 1.1-4.56) and a birth weight reduction of approximately 250 g afte r in utero exposure to carbamazepine.

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(click to filter results - removes previous filter) adverse drug reaction anticonvulsants anticonvulsants,teratogenicity of anticonvulsants,untoward effects of carbamazepine carbamazepine,toxicity review article teratogenesis teratogenic drugs

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