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Effect of Food on the Bioavailability of 100-mg Dilantin Kapseals Neurol 57:698-700,571, Cook,J.,et al, 2001 See this aricle in Pubmed Article Abstract The authors examined the effect of food on the bioavailability of Dilantin Kapseals in a nonblinded, single 100-mg dose, randomized, crossover trial. Drug was administered after an 8-hour fast and after a high-fat meal. Differences in mean di etary state values are +6% for maximum concentrations (Cmax) and -2% for area under the curve. Associated 90% CI were within US Food and Drug Administration criteria, confirming the absence of a food effect. Thus, patients may take 100-mg Dilantin Kapseal s without regard to meals.

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(click to filter results - removes previous filter) anticonvulsants anticonvulsants,absorption anticonvulsants,bioavailability anticonvulsants,blood level determination of anticonvulsants,pharmacokinetics dilantin dilantin,serum level

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