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Decreased Diffusion in Central Pontine Myelinolysis
AJNR 22:1476-1479, Cramer,S.C.,et al, 2001
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Article Abstract
Two patients with central pontine myelinolysis (CPM) were studied with diffusion-weighted MR imaging 1 week after onset of tetraplegia. In both patients, affected white matter showed hyperintensity on diffusion-weighted images associated with a decrease in apparent diffusion coefficient (ADC) values. In one patient studied serially, ADC values normalized by 3 weeks after tetraplegia. Early in the clinical course, diagnosis of CPM can sometimes be difficult. Hyperintensity on diffusion-weighte d images may therefore have diagnostic utility. Decreased lesional ADC values support the notion that CPM is a consequence of relative intracellular hypotonicity.
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central pontine myelinolysis
MRI
MRI,abnormal
MRI,ADC maps
MRI,diffusion weighted
myelinolysis,extrapontine
pons,lesion of
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