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Mitochondrial Disease and Stroke
Stroke 32:2507-2510, Martinez-Fernandez,E.,et al, 2001
See this aricle in Pubmed

Article Abstract
Of the 18 patients so far included, 3 (17%) presented lactic acid hyperproduction after physical exercise, and 6 (33%) showed deficit of the mitochondrial respiratory chain complexes. The molecular analyses have confirmed mitochondrial muta tions at base pairs 3243 (characteristic of mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes [MELAS]), 4216, and 15 928. These results suggest that ischemic stroke may be the only manifestation or the initial manifestation of a m itochondrial disorder.
 
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cerebral infarction
cerebrovascular accident
cerebrovascular accident,young adult
heralding manifestation
lactic acidemia
MELAS syndrome
mitochondrial disease
muscle biopsy

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