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Time Course of Changes in Diffusion-Weighted Magnetic Resonance Imaging in a Case of Neonatal Encephalopathy With Defined Onset and Duration of Hypoxic-Ischemic Insult
Pediatrics 108:1211-1214, Soul,J.S.,et al, 2001
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Article Abstract
The onset and duration of hypoxic-ischemic (HI) insults rarely can be determined precisely in perinatal asphyxia. The need to establish the timing of HI insults will be critical for the successful application of evolving neuroprotective the rapies that may be administered to the asphyxiated newborn. Diffusion-weighted magnetic resonance imaging has emerged as an imaging technique that can be used to identify HI brain injury before the detection of abnormalities by conventional magnetic reso nance imaging. This case illustrates the early changes in diffusion-weighted and conventional magnetic resonance imaging studies and in quantitative values of the apparent diffusion coefficient in a unique case of neonatal asphyxia in which the onset and duration of the HI insult were known.
 
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basal ganglia,lesion of
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encephalopathy,neonatal
hypoxia
hypoxia,newborn
hypoxic encephalopathy
lenticular nucleus,lesion of,bilateral
MRI
MRI,abnormal
MRI,ADC maps
MRI,diffusion weighted
thalamus,lesion of
thalamus,lesion of-bilateral

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