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The onset and duration of hypoxic-ischemic (HI) insults rarely can be determined precisely in perinatal asphyxia. The need to establish the timing of HI insults will be critical for the successful application of evolving neuroprotective the rapies that may be administered to the asphyxiated newborn. Diffusion-weighted magnetic resonance imaging has emerged as an imaging technique that can be used to identify HI brain injury before the detection of abnormalities by conventional magnetic reso nance imaging. This case illustrates the early changes in diffusion-weighted and conventional magnetic resonance imaging studies and in quantitative values of the apparent diffusion coefficient in a unique case of neonatal asphyxia in which the onset and duration of the HI insult were known. |
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basal ganglia,lesion of basal ganglia,lesion,bilateral encephalopathy,neonatal hypoxia hypoxia,newborn hypoxic encephalopathy lenticular nucleus,lesion of,bilateral MRI MRI,abnormal MRI,ADC maps MRI,diffusion weighted thalamus,lesion of thalamus,lesion of-bilateral
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