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Silent Infarcts in Children With Sickle Cell Anemia and Abnormal Cerebral Artery Velocity
Arch Neurol 58:2017-2021, Pegelow,C.H.,et al, 2001
See this aricle in Pubmed

Article Abstract
Transfusion therapy lowers the risk for new silent infarct or stroke for children having both abnormal TCD ultrasonographic velocity and silent infarct. However, those with both abnormalities who are not provided transfusion therapy are at higher risk for developing a new silent infarct or stroke than are those whose initial MRI showed no abnormality. The finding of a silent infarct reinforces the need for TCD ultrasonographic screening and consideration of transfusion therapy if the abnor malities are seen. Similarly, elevated TCD ultrasonographic velocity warrants MRI of the brain because children with both abnormalities seem to be at increased risk for developing new silent infarct or stroke.
 
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asymptomatic
blood transfusion
cerebral infarction
cerebrovascular accident
cerebrovascular accident,infancy and childhood
cerebrovascular accident,prevention of
cerebrovascular accident,silent
children
doppler
doppler,transcranial
MRI
MRI,abnormal
prevention of neurologic disorders
sickle cell disease

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