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Scleroderma "En Coup De Sabre":Pathological Evidence of Intracerebral Inflammation JNNP 70:382-385, Stone,J.,et al, 2001 See this aricle in Pubmed Article Abstract Linear scleroderma "en coup de sabre" (LScs) is associated with neurological complications, the pathogenesis of which is uncertain. A 27 year old woman is reported on who developed epilepsy and focal neurological signs in association with LSc s. Brain MRI demonstrated predominantly ipsilateral relapsing and remitting grey and white matter lesions. Analysis of CSF and pathology obtained at brain biopsy provides evidence of an inflammatory process which may be amenable to immunosuppressive trea tment.

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(click to filter results - removes previous filter) brain biopsy MRI MRI,abnormal neuropathology scleroderma scleroderma,neurologic involvement with seizure

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