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Challenging the Clinical Utility of the 14-3-3 Protein for the Diagnosis of Sporadic Creutzfeldt-Jakob Disease Arch Neurol 60:813-816,803, Geschwind,M.D.,et al, 2003 See this aricle in Pubmed Article Abstract Testing for the 14-3-3 protein is only modestly sensitive to sporadic CJD, and we caution against ruling out a diagnosis of the disease on the basis of a negative 14-3-3 result.

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