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MR Imaging and Diffusion-Weighted Imaging Changes in Metronidazole (Flagyl)-Induced Cerebellar Toxicity AJNR 24:1615-1617, Heaney,C.J.,et al, 2003 See this aricle in Pubmed Article Abstract We describe a case demonstrating reversible MR imaging findings, including diffusion-weighted imaging changes in association with metronidazole (Flagyl) toxicity. The diagnosis of metronidazole toxicity was made clinically and supported by the MR imaging findings. Quantitative apparent diffusion coefficient (ADC) maps demonstrated edema with associated increased ADC values within the dentate nuclei of the cerebellum on initial imaging. Follow-up imaging performed 8 weeks after cessation of metronidazole therapy demonstrated resolution of imaging findings, including diffusion changes.

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(click to filter results - removes previous filter) adverse drug reaction cerebellar lesion cerebellum dentate nuclei dentate nuclei,lesion of metronidazole MRI MRI,abnormal MRI,diffusion weighted MRI,disappearing lesion on neurotoxic neurotoxin

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