Neurology Specific Literature Search   
 
[home][thesaurus]
    
Click Here to return To Results

 

Neuropathological Findings in West Nile Virus Encephalitis: A Case Report
Ann Neurol 54:547-551, Agamanolis,D.P.,et al, 2003
See this aricle in Pubmed

Article Abstract
A 67-year-old woman had fever, myalgias, progressive weakness, and respiratory insufficiency. In 9 days, flaccid areflexic quadriparesis and bulbar palsy developed. She died 26 days after the onset of her illness. Serum and cerebrospinal fluid serology were positive for West Nile virus. Neuropathological study showed changes consistent with a viral encephalomyelitis, similar to poliomyelitis. The brainstem showed neuronal loss and multiple foci of necrosis. The spinal cord showed severe loss of anterior and posterior horn neurons. Immunohistochemistry identified West Nile virus antigens in the brainstem and spinal cord. Paralysis, in West Nile virus encephalitis, is caused by destruction of motor neurons.
 
Related Tags
(click to filter results - removes previous filter)

areflexia
bulbar palsy
encephalitis
encephalomyelitis
flaccid paralysis
mortality
motor neuron disease
neuropathology
neuropathology,brain
paralysis,acute areflexic
quadriparesis
spinal cord,lesion of
spinal cord,pathologic exam of
West Nile fever

Click Here to return To Results