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Riversible Diffusion MRI Abnormalities and Transient Mutism after Liver Trnasplantation
Neurol 62:981-983, Bianco,F.,et al, 2004
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Article Abstract
Transient mutism was observed in a liver transplant patient under immunosuppressant therapy with cyclosporine A and antifungal prophylaxis with amphotericin B. Fluid-attenuated inversion recovery and diffusion-weighted imagines revealed reversible bilateral symmetric hyperintensity located in the frontal motor cortex and corticospinal tracts. The MRI abnormalities may be caused by acute edema, possibly a combination of cytotocic and vasogenic edema, which resolved with a prompt change in therapy.
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adverse drug reaction
liver transplantation
motor cortex
MRI
MRI,abnormal
MRI,diffusion weighted
MRI,disappearing lesion on
mutism
transient neurologic deficit
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