Click Here to return To Results

 

Oral Simvastin Treatment in Relapsing-Remitting Multiple Sclerosis Lancet 363:1607-1608,1570, Vollmer,T.,et al, 2004 See this aricle in Pubmed Article Abstract Many drugs have been approved for relapsing forms of multiple sclerosis but are only partly effective, are injected, and are expensive. We aimed to investigate use of oral simvastatin (80 mg) in 30 individuals with relapsing-remitting multiple sclerosis. The mean number of gadolinium-enhancing lesions at months 4, 5, and 6 of treatment was compared with the mean number of lesions noted on pretreatment brain MRI scans. Number and volume of Gd-enhancing lesions declined by 44% (p<0.0001) and 41% (p=0.0018), respectively. Treatment was well tolerated. Oral simvastatin might inhibit inflammatory components of multiple sclerosis that lead to neurological disability.

Related Tags

(click to filter results - removes previous filter) gadolinium MRI MRI,abnormal MRI,contrast enhanced multiple sclerosis multiple sclerosis,relapsing multiple sclerosis,treatment of simvastatin statin therapy treatment of neurologic disorder

Click Here to return To Results