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Effect of Intravenous Corticosteroids on Death Within 14 Days in 10008 Adults with Clinically Significant Head Injury (MRC CRASH Trial): Randomised Placebo-Controlled Trial
Lancet 364:1321-1328,1291, CRASH Trial Collaborators, 2004
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Article Abstract
Our results show there is no reduction in mortality with methylprednisolone in the 2 weeks after head injury. The cause of the rise in risk of death within 2 weeks is unclear.
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head injury
head injury,management of
head injury,severe
iatrogenic neurologic disorders
mortality
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steroid therapy,CNS treatment and complications with
treatment of neurologic disorder
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