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Fatal Toxic Leukoencephalopathy: Clinical, Radiological, and Necropsy Findings in Two Patients
JNNP 76:1014-1016, Ryan,A.,et al, 2005
See this aricle in Pubmed

Article Abstract
MRI revealed diffuse white matter changes. Histologically there was widespread confluent vacuolar degeneration of the deep white matter. In both cases, there was sparing of the brain stem and cerebellar white matter. There was evidence of severe and extensive axonal injury. This pattern of radiological involvement and histological findings has not previously been reported and may reflect the presence of a yet unidentified impurity.
 
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leukoencephalopathy
leukoencephalopathy,toxic
mortality
MRI
MRI,abnormal
neuropathology
white matter disease

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