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Ambulatory Blood Pressure and The Brain, A 5-Year Follow-Up
Neurol 64:1846-1852, Goldstein,I.B.,et al, 2005
See this aricle in Pubmed

Article Abstract
Among healthy elderly individuals whose initial, average, casual blood pressure (BP) was relatively low (116.9/71.1 mm Hg), small increases in casual and 24-hour ambulatory BP measures were associated with greater brain atrophy and subcortical lesions after 5 years.
 
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blood pressure
brain atrophy
hypertension
MRI,abnormal
MRI,high signal foci on
old age,neurology of
subinsular cortex
white matter disease

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