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Progressive Multifocal Leukoencephalopathy Complicating Treatment with Natalizumab and Interferon Beta-1a for Multiple Sclerosis
NEJM 353:369-374,414,432, Kleinschemidt-DeMasters,B.K. &Tyler,K.L., 2005
See this aricle in Pubmed

Article Abstract
A 46-year-old woman with relapsing-remitting multiple sclerosis died from progressive multifocal leukoencephalopathy (PML) after having received 37 doses of natalizumab (300 mg every four weeks) as part of a clinical trial of natalizumab and interferon beta-1a.
 
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adverse drug reaction
iatrogenic neurologic disorders
interferon beta 1-a
JC virus
MRI
MRI,abnormal
multiple sclerosis
multiple sclerosis,treatment of
natalizumab
neuropathology
polymerase chain reaction
progressive multifocal leucoencephalopathy
viral infection
viral infection,CNS
white matter disease

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