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We used gradient-echo MRI to analyze spatial distribution of 321 hemorrhages in 59 patients with probable CAA-related ICH. Hemorrhagic lesions were found preferentially in the temporal (ratio of actual to expected hemorrhages = 1.37) and occipital lobes (ratio = 1.45, p < 0.0001). Within individuals, hemorrhages tended to cluster, regardless of lobe (p < 0.0001). Among subjects followed prospectively for recurrence, clustering of new symptomatic and asymptomatic hemorrhages was observed. These data suggest that regional differences within the brain play a role in the development of CAA-related hemorrhage. |
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amyloid angiopathy,cerebral intracerebral hemorrhage intracerebral hemorrhage,lobar intracerebral hemorrhage,location of intracerebral hemorrhage,recurrent magnetic susceptibility MRI MRI,abnormal MRI,gradient-echo
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