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Two Patients With COMT Inhibitor-Induced Hepatic Dysfunction and UGT1A9 Genetic Polymorphism
Neurol 65:1820-1822, Martignoni,E.,et al, 2005
See this aricle in Pubmed
Article Abstract
This suggests that UGT1A9 poor metabolizer genotype(s) may be a predisposing factor for COMT inhibitor-induced hepatoxicity.
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catechol-o-methyltransferase inhibitor
liver disease
liver function enzymes
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