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Discontinuing Prophylactic Transfusions Used to Preven Stroke in Sickle Cell Disease
NEJM 353:2769-2778,2743, The Optimizing Primary Stroke Prevention in Sickle Cell Anemia (STOP 2) Trial Investigators, 2005
See this aricle in Pubmed
Article Abstract
Discontinuation of transfusion for the prevention of stroke in children with sickle cell disease results in a high rate of reversion to abnormal blood-flow velocities on Doppler studies and stroke.
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blood transfusion
blood-flow velocity
cerebrovascular accident
cerebrovascular accident,infancy and childhood
cerebrovascular accident,prevention of
children
doppler
prevention of neurologic disorders
sickle cell disease
ultrasonography,carotid artery
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