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Alexander Disease, Ventricular Garlands and Abnormalities of the Medulla and Spinal Cord
Neurol 66:494-498,468, van der Knaap,M.S.,et al, 2006
See this aricle in Pubmed
Article Abstract
Signal abnormalities or atrophy of the medulla or spinal cord on MRI are sufficient to warrant DNA analysis for Alexander disease. Ventricular garlands constitute a new sign of the disease. Unusual phenotypes of Alexander disease are found among patients with late onset and protracted disease course.
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Alexanders disease
brainstem,lesion of
gene mutation
genetic linkage
genetic testing
GFAP gene
leukoencephalopathy
medulla oblongata
medulla oblongata,atrophy
medulla oblongata,lesion of
MRI
MRI,abnormal
MRI,spinal cord
MRI,spinal cord,increased intramedullary cord signal
spinal cord,lesion of
ventricular garlands
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