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Outcome and Symptomatic Bleeding Complications of Intravenous Thrombolysis Within 6 Hours in MRI-Selected Stroke Patients Stroke 37:852-858, Thomalla,G.,et al, 2006 See this aricle in Pubmed Article Abstract This study supports that it is safe and effective to expand the time window for IV-tPA up to 6 hours in patients with tissue at risk as defined by MRI.

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