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Thrombolysis With Alteplase for Acute Ischaemic Stroke in the Safe Implementation of Thrombolysis in stroke-Monitoring Study (SITS-MOST): An Observational Study
Lancet 369:275-282,249, Wahlgren,N.,et al, 2007
See this aricle in Pubmed

Article Abstract
These data confirm that intravenous alteplase is safe and effective in routine clinical use when used within 3 h of stroke onset, even by centers with little previous experience of thrombolytic therapy for acute stroke. The findings should encourage wider use of thrombolytic therapy for suitable patients treated in stroke centres.
 
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cerebrovascular accident
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cerebrovascular accident,thrombolytic agents in treatment
efficacy
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practice guidelines
safety
tissue plasminogen activator,intravenous
treatment of neurologic disorder

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