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Embolic Stroke Due to a Left Atrial Thrombus Two Years After Placement of an Atrial Septal Defect Closure Device
Am J Cardiol 98:1294-1296, Raghu,A.,et al, 2006
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Article Abstract
A 29-year-old woman who had undergone closure of a secundum-type atrial septal defect using the Amplatzer device 2 years previously developed acute and progressive altered mentation. Initial clinical and imaging data confirmed the diagnosis of multiple cerebral, cerebellar and brain stem emboli, and infarcts. She was treated urgently with an intra-arterial thrombolytic agent with only minimal improvement. Transesophageal echocardiography revealed a large thrombus attached to the left atrial disc of the atrial septal defect occluder, which was the source of the emboli. In conclusion, this is the first reported case, to our knowledge, of disseminated cerebral emboli and infarctions as a late complication of transcatheter closure of a secumdum-type atrial septal defect.
 
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Amplatzer device
atrial septal defect
cardiac surgery
cerebral embolism
cerebral embolism,cardiac origin
cerebrovascular accident
cerebrovascular accident,young adult
complications
iatrogenic neurologic disorders
patent foramen ovale,percutaneous closure
treatment of neurologic disorder

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