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The precise aetiology of Susac�s syndrome is still unknown and many areas have not yet been explored. Magnetic resonance imaging is the neuroimaging study of choice. Findings include multiple small hyperintense foci on T2-weighted images and contrast enhancement in white and grey matter of both supratentorial and infratentorial structures, corpus callosum and, occasionally, leptomeninges. Callosal lesions typically involve the central fibres and are probably pathognomonic for Susac�s syndrome. When assessing patients with unexplained encephalopathy involving white and grey matter, leptomeninges and corpus callosum, the findings of sensorineural hearing loss or visual disturbances may yield important clues regarding the possibility of Susac�s syndrome. |
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basal ganglia
basal ganglia,lesion of
cerebrospinal fluid,elevated protein of
corpus callosum
corpus callosum,infarction of
corpus callosum,lesion of
cyclophosphamide
deep gray nuclei
differential diagnosis
encephalopathy
fluorescein angiography
fundus,abnormality of
funduscopic exam
gadolinium
hearing loss
immunosuppressive agents
meningeal enhancement
microangiopathy,brain
microangiopathy,retina
misdiagnosis
MRI,abnormal
MRI,contrast enhanced
multiple sclerosis,differential diagnosis of
multiple sclerosis,misdiagnosis
pathognomonic
prognosis
retina,abnormal
retinal artery occlusion
retinal branch artery occlusion
retinopathy
review article
seizure
sensorineural hearing loss
steroid therapy,CNS treatment and complications with
Susac's syndrome
treatment of neurologic disorder
undiagnosed
visual field defect
visual loss
white matter disease
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