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Downbeat Nystagmus: Aetiology and Comorbidity in 117 Patients
JNNP 79:672-677, Wagner,J.N.,et al, 2008
See this aricle in Pubmed

Article Abstract
Idiopathic DBN remains common despite improved diagnostic techniques. Our findings allow the classification of �idiopathic DBN� into three subgroups: �pure� DBN (n=17); �cerebellar� DBN (ie, DBN plus further cerebellar signs in the absence of cerebellar pathology on MRI; n=6); and a �syndromatic� form of DBN associated with at least two of the following: bilateral vestibulopathy, cerebellar signs and peripheral neuropathy (n=16). The latter may be caused by multisystem neurodegeneration.
 
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adverse drug reaction
Arnold Chiari malformation
ataxia
cerebellar atrophy,secondary
cerebellar degeneration
down-beat nystagmus
nystagmus
review article
spinocerebellar ataxia
vestibulopathy

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