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Tick-Borne Encephalitis Lancet 371:1861-1871, Lindquist,L. &Vapalahti,O., 2008 See this aricle in Pubmed Article Abstract We review the epidemiological and clinical characteristics of tick-borne encephalitis, and summarize biological and virological aspects that are important for understanding the life-cycle and transmission of the virus. Tick-borne encephalitis virus is a flavivirus that is transmitted by Ixodes spp ticks in a vast area from western Europe to the eastern coast of Japan. Tick-borne encephalitis causes acute meningoencephalitis with or without myelitis. Morbidity is age dependent and is highest in adults of whom half develop encephalitis. A third of patients have long lasting sequelae, frequently with cognitive dysfunction and substantial impairment in quality of life. The disease arises in patchy endemic foci in Europe, with climatic and ecological conditions suitable for circulation of the virus. Climate change and leisure habits expose more people to tick-bites and have contributed to the increase in number of cases despite availability of effective vaccines. The serological diagnosis is usually straightforward. No specific treatment for the disease exists, and immunization is the main preventive measure.

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(click to filter results - removes previous filter) central nervous system,infection of complications disability,neurological encephalitis epidemiology of neurology flavivirus meningoencephalitis myelitis neurologic disease,diagnoses of prevention of neurologic disorders prognosis review article serologic testing tick bite tick-borne encephalitis treatment of neurologic disorder vaccine viral infection viral infection,CNS

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