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SLC01B1 Variants and Statin-Induced Myopathy -- A Genomewide Study
NEJM 359:789-799, The SEARCH Collaborative Group, 2008
See this aricle in Pubmed
Article Abstract
We have identified common variants in SLCO1B1 that are strongly associated with an increased risk of statin-induced myopathy. Genotyping these variants may help to achieve the benefits of statin therapy more safely and effectively.
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acoustic neurinoma,bilateral
adverse drug reaction
chromosome 12
complications
efficacy
genotype
myopathy
risk factors
safety
statin therapy
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