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Isolated Cortical Signal Increase on MR Imaging as a Frequent Lesion Pattern in Sporadic Creutzfeldt-Jakob Disease AJNR 29:1519-1524, Meissner,B.,et al., 2008 See this aricle in Pubmed Article Abstract A high number of patients with CJD present without basal ganglia lesions on MR imaging. Isolated cortex involvement on DWI and FLAIR should lead to suggestion of CJD, even if the disease course is only slowly progressive. Additional 14-3-3 protein in the CSF may support the CJD diagnosis.

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(click to filter results - removes previous filter) ataxia cerebral cortex dementia dementia,rapidly progressive Jakob-Creutzfeldt disease MRI MRI,abnormal MRI,diffusion weighted MRI,FLAIR protein 14-3-3,cerebrospinal fluid

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