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Asymptomatic Pontine Lesions Found by Magnetic Resonance Imaging: Are They Central Pontine Myelinolysis? J Neurol Sci 149:27-35, Kleinschmidt-Demasters,B.K.,et al, 1997 See this aricle in Pubmed Article Abstract By comparing pre- and post-mortem scans, five of the twelve unknown pontine lesions were felt to be too large to represent asymptomatic CPM. Five were thought to be incompatible with CPM base on shape and/or discohesiveness: one of these came to autopsy and showed cerebral and pontine ischemic rarefaction, not CPM. Only two of these twelve cases were felt to be asymptomatic or mildly symptomatic CPM, but have not come to autopsy. We conclude that pontine lesions found incidentally on MRI scans are a heterogeneous group, many of which are more consistent with pontine ischemic rarefaction than with asymptomatic CPM.

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