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Options to Restrict Hematoma Expansion After Spontaneous Intracerebral Hemorrhage Stroke 41:402-409, Steiner,T. &B�sel,J., 2010 See this aricle in Pubmed Article Abstract Early restriction of intracerebral hemorrhage is of paramount importance because secondary volume expansion leads to outcome deterioration and death. Although there appear to be few indications for neurosurgical measures, nonsurgical measures such as reduction of hypertension and normalization of altered coagulation seem to be beneficial. However, the routine use of coagulation factors outside of warfarin-associated spontaneous intracerebral hemorrhage cannot generally be recommended at present. The same applies for future approaches and neuroprotective therapies at this point.

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