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Evidence Report: The Efficacy and Safety of Mitoxantrone (Novantrone) in the Treatment of Multiple Sclerosis: Report of the Therapeutics and Technology Assessment Subcommittee of the American Academy of Neurology Neurol 74:1463-1470, Marriott,J.J., et al, 2010 See this aricle in Pubmed Article Abstract The risk of systolic dysfunction and leukemia in patients treated with mitoxantrone is higher than suggested at the time of the previous report, although comprehensive postmarketing surveillance data are lacking.

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(click to filter results - removes previous filter) adverse drug reaction black box warning cardiotoxicity complications congestive heart failure efficacy leukemia mitoxantrone multiple sclerosis multiple sclerosis,treatment of practice guidelines safety treatment of neurologic disorder

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